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The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug could also raise hypertension and pulse rate, and mustn't be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure, and also by you are not heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. 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It is thought that it inhibits receptors within the brain which process glutamate, which essentially alters the way ones body reacts to alcohol intake. Several of the European research has revealed a lot of promise with Acamprosate for the reason that some of the patients had a virtually double effectiveness for staying sober.